
Book Chapters Manuscripts Peer Reviewed Non-Peer Reviewed Conferences and Meetings Presentations Posters	Kentucky Injury Prevention and Research Center Publicaions DERMAL AND RESPIRATORY EXPOSURE TO ENDOSULFAN IN AGRICULTURAL WORKERS: TWO CASE STUDIES Victoria A. Brandt, University of Kentucky Chandler Medical Center, 745 Shaker Mill Rd., Bowling Green, Kentucky, 42103, Sam Moon, Duke University Medical Center, Box 3834 Durham, North Carolina, 27710, Janet Ehlers, National Institute for Occupational Safety and Health, 6476 Columbia Parkway, Cincinnati, Ohio, 45226, Mark M. Methner, National Institute for Occupational Safety and Health, 6476 Columbia Parkway, Cincinnati, Ohio, 45226, and Tim Struttmann, University of Kentucky Chandler Medical Center, 333 Waller Ave., Lexington, Kentucky, 40504. North American Agromedicine Consortium. Raleigh, NC; Sep 1999. Endosulfan is an organochlorine insecticide that does not require user certification. In 1993, one confirmed case and one possible case of endosulfan poisoning in agricultural workers occurred in two southeastern states. Investigations revealed that one case was fatal and one non-fatal case resulted in permanent neurological impairment. Both involved dermal and respiratory exposure to endosulfan. The fatal case revealed the agricultural worker was applying three pesticides but spilled concentrated endosulfan on one hand. Of the three pesticides used endosulfan was the most toxic. Analysis of blood samples revealed a total endosulfan level of 0.84mg/L. Endosulfan cannot be manufactured in the United States and is under regulatory control in several countries. It is a neurotoxin that often results in seizures, as in the non-fatal case described here, and causes respiratory paralysis after exposures to high levels. Endosulfan is used on cotton, tobacco, fruit and vegetable crops. All previously reported human deaths from endosulfan in the United States have involved ingestion. Pesticide poisoning and an individual's susceptibility depends upon many factors. Similarities in these cases address the need for pesticide prevention strategies among agricultural workers, including wearing the proper personal protective equipment during handling. Comments to Mark Schneider, Last Modified: July 9, 2001 by JP Copyright ©2000, University of Kentucky Chandler Medical Center Terms, Conditions & Privacy Statement

Kentucky Injury Prevention
and Research Center Publicaions

DERMAL AND RESPIRATORY EXPOSURE TO ENDOSULFAN IN AGRICULTURAL WORKERS: TWO CASE STUDIES

Victoria A. Brandt, University of Kentucky Chandler Medical Center, 745 Shaker Mill Rd., Bowling Green, Kentucky, 42103, Sam Moon, Duke University Medical Center, Box 3834 Durham, North Carolina, 27710, Janet Ehlers, National Institute for Occupational Safety and Health, 6476 Columbia Parkway, Cincinnati, Ohio, 45226, Mark M. Methner, National Institute for Occupational Safety and Health, 6476 Columbia Parkway, Cincinnati, Ohio, 45226, and Tim Struttmann, University of Kentucky Chandler Medical Center, 333 Waller Ave., Lexington, Kentucky, 40504.

North American Agromedicine Consortium. Raleigh, NC; Sep 1999.

Endosulfan is an organochlorine insecticide that does not require user certification. In 1993, one confirmed case and one possible case of endosulfan poisoning in agricultural workers occurred in two southeastern states. Investigations revealed that one case was fatal and one non-fatal case resulted in permanent neurological impairment. Both involved dermal and respiratory exposure to endosulfan. The fatal case revealed the agricultural worker was applying three pesticides but spilled concentrated endosulfan on one hand. Of the three pesticides used endosulfan was the most toxic. Analysis of blood samples revealed a total endosulfan level of 0.84mg/L. Endosulfan cannot be manufactured in the United States and is under regulatory control in several countries. It is a neurotoxin that often results in seizures, as in the non-fatal case described here, and causes respiratory paralysis after exposures to high levels. Endosulfan is used on cotton, tobacco, fruit and vegetable crops. All previously reported human deaths from endosulfan in the United States have involved ingestion. Pesticide poisoning and an individual's susceptibility depends upon many factors. Similarities in these cases address the need for pesticide prevention strategies among agricultural workers, including wearing the proper personal protective equipment during handling.

Kentucky Injury Prevention and Research Center Publicaions

DERMAL AND RESPIRATORY EXPOSURE TO ENDOSULFAN IN AGRICULTURAL WORKERS: TWO CASE STUDIES

Kentucky Injury Prevention
and Research Center Publicaions